Vitamin E with Selenium: Why You Should Take Them Together

Last Updated on October 5, 2022 by Monica Nelson

Vitamin E and selenium are two essential vitamins and minerals that your body needs for numerous processes and functions. Both are potent antioxidants that help boost the immune system and enable the body to fight cell damage from oxidative stress. Without these essential nutrients, your health would seriously suffer.

While vitamin E and selenium each have individual roles, they provide enhanced benefits combined. Keep reading to find out more about the health benefits of each and what happens when they are taken together.

The Benefits of Vitamin E

Vitamin E isn’t a singular vitamin as it may seem, but a group of fat-soluble compounds. It is found in foods like vegetable oils, meat, poultry, eggs, fruit, vegetables, and nuts or can be taken as a supplement.

Vitamin E is required for healthy eyes and skin, a robust immune system, and cellular signaling. It also acts as a powerful antioxidant to help the body fight cell damage and ward off disease.

Find out more about the main benefits of vitamin E supplements below.

A potent antioxidant

Vitamin E is most well known for its powerful antioxidant effects. During a state of oxidative stress, there is an imbalance between antioxidants in the body and highly-reactive free radical molecules. These cause cell damage which increases the risk for disease and contributes to aging.

Vitamin E boosts antioxidant defenses in the body, neutralizing the harmful effects of free radicals and protecting cells from damage 1. In doing so, vitamin E has been found to help protect against cognitive conditions like Alzheimer’s, reduce inflammation, boost immune function and improve lung health and asthma symptoms 2.

Reduce the risk of heart disease

Risk factors for heart disease, a leading cause of death worldwide, include high blood pressure and high levels of LDL (bad) cholesterol. Evidence suggests that vitamin E supplements are effective at lowering the risk for heart disease by reducing both these risk factors 3

Healthier skin

Vitamin E is commonly used to boost skin health and is often found in skin products, and for a good reason. By reducing oxidative stress and preventing damage from free radicals, it can help fight inflammation and treat skin disorders like eczema, improve the overall appearance of the skin, and fight the effects of UV sun damage 4.

Lung function

Some studies have found that vitamin E supplements can help improve lung function and symptoms in people with asthma by reducing oxidative stress and inflammation 5.

The Benefits of Selenium

Now it’s time to look at the importance of the lesser known mineral, selenium. While it is only needed in small amounts, it is still essential to get enough to support numerous body processes, including metabolism, DNA synthesis, immune function, and thyroid function.

Selenium is found in trace amounts in nuts, seafood, and meats. Like vitamin E, it also packs some serious antioxidant punches, helping strengthen the body’s natural defenses.

Here are a few of the main benefits of selenium supplements.

Fights oxidative stress

Selenium helps protect against cell damage and chronic conditions associated with oxidative stress, such as cancer and Alzheimer’s, by keeping the number of free radical molecules low 6.

Supports a healthy heart

Low selenium levels have been linked to an increased risk of heart disease, mainly due to its ability to reduce oxidative stress and inflammation 7. These are both significant risk factors that increase the buildup of plaque in arteries which can lead to the hardening and narrowing of blood vessels and result in heart attacks or stroke.

Proper thyroid function

Selenium is present in very high concentrations in the thyroid gland, where it plays a crucial role in producing thyroid hormones and protecting it from oxidative stress. The thyroid is essential for keeping your metabolism in check and controls growth and development.

Selenium deficiency puts you at higher risk for thyroid conditions like hypothyroidism, Hashimoto’s disease, and thyroiditis. But by increasing levels of selenium through supplementation, symptoms of these conditions may improve, and thyroid function can be restored 8.

Improves asthma symptoms

Asthma is a common breathing condition that causes shortness of breath and wheezing and is sometimes life-threatening. The causes of asthma vary, but it is known to be linked to increased inflammation and oxidative stress, as well as low selenium levels.

As such, scientists have found that reversing the effects of selenium deficiency through supplementation can minimize cell damage in the lungs and calm inflammation, improving lung function and asthma symptoms 9.

Vitamin E and Selenium: The Perfect Duo

As you may have noticed, both vitamin E and selenium possess strong antioxidant capabilities. Taken together, their combined antioxidant effects are vastly more significant than if taken alone, helping your body fight oxidative stress and disease more effectively!

The combination of Performance Lab NutriGenesis Multi and PL-Immune provides your body with an effective dose of vitamin E and selenium and allows you to bridge other nutritional gaps by delivering other daily essentials for better overall health and immunity.


Vitamin E is an important vitamin and antioxidant that protects against oxidative damage, boosts immune function, reduces the risk of heart disease, and maintains healthy skin.

Similarly, selenium is a mineral that possesses antioxidant properties that help prevent cell damage and reduce the risk of diseases like cancer. It also helps reduce the risk of heart disease and supports proper thyroid function.

When vitamin E is combined with selenium, they work together to enhance their effects further, providing a more powerful supplement to improve health and immune function.


  1. Aghadavod, Esmat, et al. “Effects of high-dose vitamin E supplementation on markers of cardiometabolic risk and oxidative stress in patients with diabetic nephropathy: A randomized double-blinded controlled trial.” Iranian journal of kidney diseases 12.3 (2018): 156.
  2. Browne, Declan, et al. “Vitamin E and Alzheimer’s disease: what do we know so far?.” Clinical interventions in aging 14 (2019): 1303.
  3. Asbaghi, Omid, Razieh Choghakhori, and Amir Abbasnezhad. “Effect of Omega-3 and vitamin E co-supplementation on serum lipids concentrations in overweight patients with metabolic disorders: A systematic review and meta-analysis of randomized controlled trials.” Diabetes & Metabolic Syndrome: Clinical Research & Reviews 13.4 (2019): 2525-2531.
  4. Teo, Cheryl Wei Ling, et al. “Vitamin E in Atopic Dermatitis: From Preclinical to Clinical Studies.” Dermatology 237.4 (2021): 553-564.
  5. Ghaffari, Javad, et al. “Vitamin e supplementation, lung functions and clinical manifestations in children with moderate asthma: A randomized double blind placebo-controlled trial.” Iranian Journal of Allergy, Asthma and Immunology (2014): 98-103.
  6. Schnabel, Renate, et al. “Selenium supplementation improves antioxidant capacity in vitro and in vivo in patients with coronary artery disease: The SElenium Therapy in Coronary Artery disease Patients (SETCAP) Study.” American heart journal 156.6 (2008): 1201-e1.
  7. Flores-Mateo, Gemma, et al. “Selenium and coronary heart disease: a meta-analysis.” The American journal of clinical nutrition 84.4 (2006): 762-773.
  8. Toulis, Konstantinos A., et al. “Selenium supplementation in the treatment of Hashimoto’s thyroiditis: a systematic review and a meta-analysis.” Thyroid 20.10 (2010): 1163-1173.
  9. Gazdik, F., J. Kadrabova, and K. Gazdikova. “Decreased consumption of corticosteroids after selenium supplementation in corticoid-dependent asthmatics.” Bratislavske Lekarske Listy 103.1 (2002): 22-25.

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